SLC12A5 and epilepsy: KCC2 phosphorylation has been demonstrated to impact neuronal excitability, having possible disease relevance for epilepsy, with key discoveries made by several investigators, amongst them the groups of Kristofer Kahle, Stephen Moss, Eric Delpire, and other investigators with distinguished records (Strange et al., 2000; Woo et al., 2002; Zhu et al., 2008; Lee et al., 2010, 2011; Kahle et al., 2013, 2014b, 2016a; Kelley et al., 2018; Pisella et al., 2019; Watanabe et al., 2019; Kontou et al., 2021).