TYRP1 and Parkinson disease: Indeed, as CQ and HCQ inhibit CatB, a protein implicated in the pathogenesis of both RA and PD, it is likely that these drugs inhibit CatB (Hashimoto et al., 2001; Tsujimura et al., 2015; Mahoney-Sánchez et al., 2021; Zhao et al., 2022).