The SASP signature after TNFα/IFN‐γ exposure, including IL‐6, IL‐8, CCL2, IL‐1β, and PAI‐1, overlaps the cytokine profile observed in severe cases of COVID‐19 (Bartleson et al., 2021; Moore & June, 2020). The gene discussed is SERPINE1; the disease is COVID-19.