IL6R and COVID-19: The efficacy of these interleukin-6 receptor antagonists, including improved outcome and survival, in severe and critically ill patients with COVID-19 who were receiving organ support in intensive care with treatment with the tocilizumab and sarilumab (IL-6 receptor antagonists), was assessed in 803 adult patients: 353 patients received tocilizumab, 48 sarilumab, and 402 were enrolled to the control group.