In the current research, we probed the impacts of RBP-J OE Mφ-Exos (exosomes derived from RBP-J-overexpressed macrophages) on glioma cell proliferation and invasion and compared them with Exos from THP-1-like macrophages (WT Mφ-Exos) [30]. This evidence concerns the gene RBPJ and glioma.