Several genes that have been reported in NSCLC [13, 20, 21] were found to be co-occurred with EGFR, including APC (10.6%), CTNNB1 (10.6%), PIK3CA (9.1%), MED12 (7.6%), ARID1A (6.1%), PARP1 (6.1%), SETD2 (6.1%), CDKN2A (4.5%). The gene discussed is PIK3CA; the disease is non-small cell lung carcinoma.