Having established that MBNL1 and CUGBP1 colocalise closely in SGs, and that there may be subtle changes in the dynamics of MBNL1 in SGs associated with the presence of CUGexp RNA, we next sought to investigate the relationship between these two DM1-associated proteins in SGs. The gene discussed is MBNL1; the disease is myotonic dystrophy type 1.