A significant increase in the half-time of recovery for GFPMBNL1 in P-bodies was seen for DM1 cells compared to controls, indicating an altered relationship of MBNL1 with P-bodies associated with DM1 (3.4±2.3 s for DM1, 2.0±1.2 s for control). The gene discussed is MBNL1; the disease is myotonic dystrophy type 1.