The role of five of them (LAMB2, SERPINEE1, ITGB1, TNC, and LAMA5) in tumor growth has been well established (Angel et al., 2020; Bartolini et al., 2016; Long et al., 2016; Wang et al., 2021; Yang et al., 2020b). The gene discussed is LAMA5; the disease is neoplasm.