The higher the immune score and stromal score are, the higher the degree of non-tumor cell infiltration in tumor tissue is. Immune cell score (R = − 0.26, P = 0.00041) and stromal cell score (R = − 0.26, P = 0.00066) showed a negative correlation with the expression of YOD1 (Fig. 5D, E). This evidence concerns the gene YOD1 and neoplasm.