TP53 and pancreatic adenocarcinoma: After understanding the prognostic role of YOD1 in PAAD, we will explore the biological function of YOD1 in PAAD. GO and KEGG enrichment results were displayed in the first 30 bits of NES by bubble diagram. GO analysis showed that the high expression of YOD1 was correlated with biological functions such as metastasis, gemcitabine resistance and transcription (Fig. 6A). KEGG pathway analysis showed that the high expression of YOD1 was correlated with other pathways such as base excise and repair, p53 signaling pathway, RNA degradation, cell–cell adhesion and connection (Fig. 6B).