As shown in Additional file 1: Fig. S3, the high expression of YOD1 in PAAD is highly correlated with adhesion, metastasis, invasion, Gefitinib chemotherapy resistance, DNA repair, tumor hypoxic microenvironment and p53, Notch, NRG1, MYC, EGFR, Hippo signaling pathway. This evidence concerns the gene NRG1 and neoplasm.