Since our METABRIC analysis showed that 4EBP1 mRNA has the highest expression in the TNBC subtype (Fig. 7A) and that a positive correlation between 4EBP1 and c-MYC mRNA exist in breast cancer (Fig. 7C), we were next interested in determining the role of 4EBP1 in the miR-3189-3p-mediated downregulation of c-MYC protein in MDA-MB-231 cells. The gene discussed is MYC; the disease is breast carcinoma.