To further explore if RGD-PLT@PLGA-FE treatment promotes cerebral blood flow of stroke mice, laser speckle imaging was used to measure the cerebral blood flow in sham mice and ischemic areas of stroke mice that treated with 10% sucrose, FE only, PLGA-FE, PLT@PLGA-FE, RGD-PLT@PLGA, and RGD-PLT@PLGA-FE. Here, NAAA is linked to stroke disorder.