Patients with early stage colon cancer i.e. stage I & IIA, where according to the surgical stage grouping the cancer is restricted to the walls of the colon and has not spread to nearby lymph nodes or distant organs, showed higher NOSTRIN expression compared to advanced disease stages i.e. stage IIB, IIIB, IIIC (our data), where the tumor has spread to nearby lymph nodes & stage IV where the tumor has also spread to some distant organs along with the lymph nodes. This evidence concerns the gene NOSTRIN and malignant colon neoplasm.