As shown in Fig. 2C, the enriched KEGG pathways involved in c-Fos mainly contained MAPK signaling pathway, PI3K-Akt signaling pathway, TNF signaling pathway, non-alcoholic fatty liver disease, C-type lectin receptor signaling pathway and IL-17 signaling pathway. The gene discussed is CLEC4D; the disease is metabolic dysfunction-associated steatotic liver disease.