Among the thirteen SE-lncRNAs analyzed, six SE-lncRNA and their corresponding coding transcripts were both significantly upregulated in leiomyomas (RP11-353N14.2/CBX4, SOCS2-AS1/SOCS2, RP1-170O19.14/HOXA11, CASC15/PRL, EGFLAM-AS1/EGFLAM, RP11-225H22/NEURL1) (Fig. 5A–F), while six SE-lncRNAs with their corresponding protein coding genes were both significantly downregulated in leiomyomas (RP5-1086K13.1/CD58, AC092839.3/SPTBN1, RP11-69I8.3/CTGF, TM4SF1-AS1/TM4SF1, RP11-373D23/FOSL2, and RP11-399K21.11/COMTD1) (Fig. 5G–L). The gene discussed is CD58; the disease is leiomyoma.