This GWAS identified rs1992269 located at 18p11.32, and meta-analysis after stratification of the discovery and replication cohorts by APOE ε4 carrier and non-carrier status identified rs802571 in the intron of CNTNAP2 and rs11613092 in the intergenic region between SUDS3 and SRRM4. However, a meta-analysis of APOE ε4 carriers did not yield any significant SNPs associated with AD. This evidence concerns the gene APOE and Alzheimer disease.