Grade 3/4 TRAEs occurred in 19 (41.3%) of 46 patients, with the most common being neutropenia (30.4%), thrombocytopenia (19.6%), elevated aspartate aminotransferase (17.4%), elevated alanine transaminase (17.4%), and leukopenia (13.0%) (Table 3). This evidence concerns the gene GPT and Decreased total leukocyte count.