Figure 4 shows the association of variants in different EGFR regions with risk of stroke. This illustrates that there was no clear difference in strength of association with stroke for EGFRs 1–9 and 18–34 but that EGFRs 10–17 seemed to be associated with a lower stroke risk compared with domains 3–4 (Figure 4). When using EGFRs 3–4 as the reference, the risk of stroke associated with EGFRs 12–17 was almost 80% lower (HR: 0.23, 95% CI: 0.12–0.47, p = 7.7 × 10−5). This evidence concerns the gene EGFR and Stroke.