In this study, we investigated the kinetics of IgG and IgA responses to S1, S2, RBD, and N protein, ACE2 receptor blocking antibodies and antibodies against SARS-CoV-2 variants, in individuals at 4 and 12 weeks following natural infection and in those who had a single dose of the AZD1222. The gene discussed is CD79A; the disease is infection.