The aim of the study was: (1) to evaluate the serum levels of lipocalin-2 and visfatin in patients with alopecia areata in comparison with healthy controls; (2) to determine the serum levels of total cholesterol, low-density lipoprotein cholesterol (LDL-cholesterol), high-density lipoprotein cholesterol (HDL-cholesterol), triglycerides, fasting glucose, insulin, c-peptide, and homeostasis model assessment for insulin resistance (HOMA-IR) in patients with alopecia areata compared to healthy controls. The gene discussed is INS; the disease is Insulin resistance.