IGF2BP1 and leiomyoma: TGFBR2 is a receptor of a secreted polypeptide TGF-beta2, which regulates leiomyoma growth [27].The IGF2BP1, an oncofetal RNA-binding protein, has been identified to play an important role in cell proliferation and growth of normal tissues and tumor tissues, as well as tumor cell adhesion, apoptosis, migration, and invasion [28].