Similar to PD, GBA variants predispose to an earlier age at onset, more pronounced disease severity/progression and rather “pure” form of DLB without concomitant Alzheimer’s profile as defined by CSF p-tau/Aβ1-42 ratio (Nalls et al. 2013; van der Lee et al. 2021). The gene discussed is GBA1; the disease is Lewy body dementia.