CLEC4D and infection: In the KEGG and IPA pathway enrichment for Leptospira-infected BMDMs after the initial infection (at 2 h), PRR-signaling pathways including the “C-type lectin receptor signaling pathway,” “NOD-like receptor signaling pathway,” and “TLR signaling pathway” were identified in nonpathogenic Leptospira-infected BMDMs, whereas the “NOD-like receptor signaling pathway” and “TLR signaling pathway” were found in pathogenic Leptospira-infected BMDMs.