CD4 and type 1 diabetes mellitus: As shown in the heatmap (Figure 2C, arrowhead), one T1D risk allele, rs11574435-T, which is in strong LD (r2=0.95) with the T1D GWAS SNP rs113010081 (Onengut-Gumuscu et al., 2015), is associated with a higher percentage of many CCR5+ CD4+ T cell traits and a lower percentage of CCR5− CD4+ T cell traits.