As demonstrated from our results, the identified candidate NAFLD-related TFs: Tcea1, Rbbp4, ILF2, Npm1, Ruvbl2, Npm1, Nucb1, Pc, Pura, Sra1, Preb, and Carhsp1 (Table 1) are found in the same clusters with already well-known NAFLD-related proteins (Figure 3F), enhancing their potential implication in NAFLD. Here, NUCB1 is linked to metabolic dysfunction-associated steatotic liver disease.