Immunohistochemistry (IHC) staining of 39 clinical human cervical tumor tissues revealed that both METTL3 and CDC25B are moderately or highly expressed in most of the cervical cancer samples, whereas their expression is weak or not detectable in the superficial or intermediate squamous epithelial cell layer of the cervix (Fig. 6E). The gene discussed is METTL3; the disease is cervical cancer.