A Cox regression analysis performed to explore the disease-free survival impact of the hub genes in MM patients demonstrated that the SNRPD2 (HR = 1.603, 95% CI: 1.236-2.079, P < 0.001), SNRPD3 (HR = 1.174, 95% CI: 0.904-1.525, P = 0.230), and EIF4A3 (HR = 1.656, 95% CI: 1.289-2.126, P < 0.001) were associated with the DFS (Supplementary Table 1). Here, SNRPD3 is linked to Miyoshi myopathy.