By detecting the plasma concentrations of thrombin−antithrombin (TAT) complexes, platelet factor 4 (PF4), and D-dimers in AAA patients, it was found that an increase in D-dimers and TAT complex levels can predict progression of the disease and the growth of aneurysms in patients with AAA or subaortic dilatation (Sundermann et al., 2018). This evidence concerns the gene PF4 and triple-A syndrome.