TP53 and neoplasm: The driver gene meta-analysis of 229 patients identified 7 driver genes (BAP1, NF2, TP53, SETD2, LATS2, DDX3X and SETDB1) which were significant in two SMG approaches (q-value of < 0.05) (Fig. 3A and Additional file 6: Table S5), all of which have previously been reported as MPM tumour drivers [3, 4].