UBE3A and Angelman syndrome: This was indeed the case; the paper first describing UBE3A was the most cited paper related to UBE3A and AS; however, it did not come up when we searched only for “Angelman syndrome”. By combining the results of our original search with “UBE3A” and “E6AP” in Web of Science, we identified the most cited papers per 5-year periods, from 1976 to 2021.