Although neither neuronal loss nor neurodegeneration have been identified in PD in such location, as is the case in multiple well-known regions belonging to CAN26, alpha-synuclein aggregates and Lewy neurites, and to a much lesser extent Lewy bodies43, as well as denervation of cerebellar dopamine receptors44 have been detected in the cerebellum of PD patients. This evidence concerns the gene SNCA and Parkinson disease.