Although the majority of large studies find a clear association between MBOAT7 loss of function and NAFLD progression, it is important to point out that not all studies have found statistically significant associations (24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35). The gene discussed is MBOAT7; the disease is metabolic dysfunction-associated steatotic liver disease.