To identify potential cytokine‐production patterns in WT and KO mice in response to N67C or YM infection, we infected WT, Ifih1–/–, Mavs–/–, Mb21d1–/–, and Tmem173gt mice with either N67C or YM, then examined the serum amounts of IFN‐α, IFN‐β, and IL‐6 during the course of each infection. This evidence concerns the gene MAVS and infection.