In contrast, we did not observe any appreciable difference in the percentages of the CD11b+Ly6CloLy6G+ cells of resistant (Tmem173gt, Mb21d1–/–, Myd88–/–, and Mavs–/–Il6–/–) and sensitive (WT and Mavs–/–) mice (Figure 6C,D; Figure S6F, Supporting Information), suggesting that late IL‐6 mainly induces and expands CD11b+Ly6ChiLy6G– proinflammatory monocytes to dampen anti‐malaria immune responses. Here, MYD88 is linked to malaria.