In subgroups divided by the expression levels of TGFBI, tumor immunosuppression‐related pathways, such as P53 signaling pathways, phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling pathways, cell cycle pathways, tumor necrosis factor (TNF)‐κB signaling pathways, Janus kinase–signal transducer and activator of transcription signaling pathways, and apoptosis pathways, were enriched in high‐level expression groups. The gene discussed is TNF; the disease is neoplasm.