The expressions of five genes (SPP1, TGFBI, IFI30, C1QC, and EREG) are shown by a t‐SNE plot in Figure S2, indicating that TGFBI+ TAMs, SPP1+ TAMs, and CD16+ blood‐derived monocyte IFI30+ TAMs are three significantly different TAM subgroups in six cancers (AML, BRCA, GBM, HNSCC, LUAD, and MEL). The gene discussed is EREG; the disease is head and neck squamous cell carcinoma.