damage to the physical properties of the viral envelope (Kim et al. 2013)inhibite influenza A replication (Ling et al. 2012)remarkably downregulate TLR4 protein levels through 67LR/Tollip, decrease MPO activity and inflammatory cytokine levels (Xu et al. 2017)inhibit the early stage of infections, such as attachment, entry, and membrane fusion, by interfering with viral membrane proteins (Kaihatsu et al. 2018)inhibit NA activities (Ide et al. 2016). This evidence concerns the gene TLR4 and infection.