PNPLA3 and neonatal abstinence syndrome: Of the five major SNPs (PNPLA3_rs738409 C > G, TM6SF2_rs58542926 C > T, SREBF2_rs133291 C > T, MBOAT7_rs641738 C > T, and HSD17B13_rs72613567 adenine insertion [A-INS]), only the prevalence of PNPLA3_rs738409 C > G significantly differed among the NAS subgroups in both the HC and LC groups.