CRP and rheumatoid arthritis: ESR, CRP and RF are commonly used clinical efficacy evaluation indicators of rheumatoid arthritis, and their levels are positively correlated with disease severity, which can reflect disease activity and patient prognosis.14 Earlier, Kang X et al.15 observed that the levels of rheumatoid factor (RF) and C-reactive protein (CRP) decreased significantly in 20 patients after one month of treatment with disease modifying anti-rheumatic drugs and glucocorticoids.