As a new tumor marker, it is highly expressed in most ovarian cancer tissues.7 In this study, serum miR-21, HE4, and CA125 expression in ovarian cancer patients were measured to analyze the value of simultaneous detection of miR-21, HE4, and CA125 in predicting postoperative recurrence and metastasis of ovarian cancer. Here, WFDC2 is linked to ovarian carcinoma.