AKT1 and hypertrophic cardiomyopathy: Furthermore, KEGG pathway analysis identified 7 pathways with significant enrichment (Figure 3B), such as hypertrophic cardiomyopathy, Jak-STAT signaling pathway, cytokine–cytokine receptor interaction, PI3K-Akt signaling pathway, pathways in cancer, proteoglycans in cancer, and Ras signaling pathway.