Regarding its expression in the fetal DS brain, DYRK1A resulted as being overexpressed (RNA) at GW15–GW37 (El Hajj et al., 2016) and GW20 (Guimera et al., 1999), and DYRK1A protein was overexpressed at GW23 (Park et al., 2010). This evidence concerns the gene DYRK1A and Dravet syndrome.