Finally, magnesium regulates the immune system in a variety of ways by orchestrating the activity of immune cells such as neutrophils and macrophages (39), activating T cells via MagT1 (40), and regulating vitamin D activity (41), hence improving the first line of defense in response to pathogens invasion and acting against viral infections like COVID-19 (38). This evidence concerns the gene MAGT1 and COVID-19.