CD163 and neoplasm: We then computed the relative change in each cell phenotype of non-responders compared to responders: neutrophils, CD163+PD-L1-HLAhi macrophages, CD163- macrophages, stromal cells, plus all lymphocytes and all macrophages (except CD163+PD-L1-HLADRlo subtype) were prevalent in R, whereas all tumor cells and CD163+PD-L1-HLADRlo macrophages were prevalent in NR (Figure 3D).