However, the patient was negative for P-ANCA, C-ANCA, ANCA-MPO, ANCA-PR3, and ACA by relevant laboratory antibodies, although some studies have demonstrated that the relevant immunological markers may be negative if the aortitis is in a nonacute phase, and based on the patient's family history and angiographic findings, the possibility of bilateral common carotid artery occlusion due to aortitis cannot be excluded [24]. The gene discussed is MPO; the disease is aortitis.