Interestingly, ATX antigen levels did not correlate significantly with tMCA levels in pediatric ASC patients with pruritus (Spearman r = 0.37; p = 0.4972) but with tMCA levels in patients without pruritus (Spearman r = 0.87; p = 0.0001). The gene discussed is ENPP2; the disease is Tako-tsubo cardiomyopathy.