PVAS values did not correlate with tBA levels (Spearman r = 0.05, p = 0.9316), tMCA levels (Spearman r = 0.62, p = 0.3787) or ATX values (Spearman r = 0.38, p = 0.4722) in pediatric patients with ASC and pruritus. The gene discussed is ENPP2; the disease is Tako-tsubo cardiomyopathy.