CD4 and tuberculosis: However, the sensitivity of Xpert Ultra was higher than TB-lipoarabinomannan (TB-LAM) assay and reached 50% in patients positive for HIV, with CD4 <100 cells/ml, thus suggesting that Xpert Ultra on urine samples could be an alternative approach for individuals with advanced HIV infection and unable to produce sputum samples (Andama et al., 2020).