Martus JA, et al. showed that the main risk factors for EOS were maternal history of abortion, WBC >15 x 109/L, premature rupture of membranes >18 hours, C-reactive protein (CRP) >1.5 mg/l, body temperature >38°C, prenatal use of antibiotics, chorioamnionitis, endometritis, neonatal low Apgar score and low gestational age (the incidence of full-term infants was 0.6% and the incidence of premature infants <28 weeks was 16.6%). This evidence concerns the gene CRP and endometritis.