Consistently, the expression of viral RNAs and interferon beta (IFN-β) after viral infection was diminished in the mice lungs in the 3D8 scFv-pretreatment group compared with the mice’s lungs in the other groups, as demonstrated by the reduced expression of HA (68%), NP (71%), and IFN-β (51%) in the mice lungs in the 3D8 scFv-pretreatment group compared with those of the mice in the PBS-pretreatment group (Figure 4E). Here, IFNB1 is linked to viral infectious disease.