TNFRSF14 and infection: In WT C57BL/6 mice, the observation that a higher colocalization of the virus and dendritic cells at 24 h after infection was followed by a higher viral titer in tissue at 48 h after infection suggested that because of the capacity of the virus to directly infect dendritic cells in HVEM−/− mice, the virus might be trapped in local epithelial tissue by the host-stress response, including inflammatory and innate immune responses triggered by dendritic cells and other immune cells residing in epithelial tissues.