Although the combination of eight mRNAs have been suggested to be used as biomarkers for EBL, it is unclear whether these mRNAs are EBL-specific, because they have been reported in various other diseases; for example, CXCL8 has been reported to mediate the initiation and development of breast cancer in humans [38] and is increased in bovine mastitis [51]. This evidence concerns the gene CXCL8 and breast cancer.