Among the GBM biopsies, we found a diversified Gal-1 expression profile with recurrent GBM tissues expressing significantly higher levels of Gal-1 than primary GBM tissues (45% of recurrent GBM tissues expressed medium or high levels of Gal-1, compared with 20% of primary GBM tissues; Figure 7). The gene discussed is LGALS1; the disease is glioblastoma.