Some of these systemic symptoms resemble those of MS/CFS, and chronic epipharyngitis is reported to activate epipharyngeal inner immunity and produce neuroexcitatory molecules, such as TNF-α, IFN-γ, and IL-1, which activate the immune system of the brain, resulting in low-grade inflammation in the brain associated with MF/CFS [12,13,34,35,36,37]. The gene discussed is TNF; the disease is myalgic encephalomeyelitis/chronic fatigue syndrome.